The arrival of £27million Edin Dzeko from Wolfsburg has given the City boss an embarrassment of attacking riches.
In addition to Dzeko, Mancini can also call upon the services of Carlos Tevez, Mario Balotelli, David Silva and Adam Johnson.
"Sometimes it will be possible to play all of them," said Mancini."Any team must have balance. But when we played Birmingham and Blackburn earlier in the season, we spent 90 minutes in their box without scoring.
"In games like that it will be possible."