Manchester United and Manchester City are 5/2 joint favourites for the FA Cup.
Liverpool and Spurs both bowed out in shock defeats at Oldham and Leeds respectively while holders Chelsea were minutes away from crashing out at Brentford before Fernando Torres goal earned them a replay.
Chelsea, who are ranked third favourites at 9/2, will travel to Middlesbrough if they overcome Brentford at Stamford Bridge. Arsenal, who take on Blackburn at the Emirates, are further back at 11/2.